Fecal Peritonitis in Rats



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Aly Saber, Mohammed H. Shekidef, Mohamed H. El-Daharawy

Journal of Advanced Veterinary Research 1, 8-12

Abstract

In this study, cecal ligation and puncture were performed in 75 Sprgue-Dawley rats. Peritoneal lavage was performed using 10 ml of povidone-iodine as 1% concentration in group A, while the same volume of 50% of honey diluted in distilled water was used in group B. Group C was used as a control. The overall mortality was 32% in group A (8/25), 12% in group B (3/25) and 60% in group C (15/25). Tissue toxicity was found to outweigh bactericidal effects. Honey was tested for its broad-spectrum antibacterial activity without adverse effects. So, we concluded that honey might be used as a peritoneal lavage solution with no side effects.

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