Postdoctoral Fellows are appointed for up to three years and will work closely with a leading Research Scientist or Engineer in their respective field. They carry out innovative, impactful research of strategic importance to CSIRO with the possibility of novel and important scientific outcomes. They present the findings in appropriate publications and at conferences.
CSIRO Manufacturing is seeking a Postdoctoral Fellow to join the 4D cell culture group led by CSIRO Science Leader Prof Sally McArthur. The group is part of the Cell Biology Theme within the Biomedical Manufacturing Program, and the project will be undertaken in collaboration with optical imaging and spectroscopy researchers at Swinburne University of Technology.
This project will address the fundamental scientific and technical challenges associated with imaging 3D cell culture systems in real-time to enable the monitoring of cell viability, cell-cell signalling, scaffold/matrix organisation and the influence of biological and external stimuli (i.e. drugs) on engineered tissues. In order to address these fundamental questions the project will explore the application of existing and emerging imaging techniques in a multi-modal platform for monitoring 3D tissues and cell cultures. Current modalities targeted for inclusion are fluorescence lifetime imaging (FLIM), non-linear optical microscopies like optical coherence spectroscopy (OCT) and coherence anti-Stokes Raman spectroscopy (CARS). Additionally the project will explore multiphoton imaging and light sheet microscopy.
Your duties will include:
- Implementing and integrating a range of optical imaging and detection techniques to undertake real time monitoring of 3D cell culture systems.
- Exploiting changes in the physical and chemical properties of native markers produced by cells or nanoparticle-based biosensors to deliver novel imaging modalities.
- Developing a data integration platform to enable the collection, comparison and optimisation of analysis techniques for 4D cell culture systems.
- Building and delivering project outcomes with research partners at Swinburne University of Technology and other organisations globally.
- Undertaking regular reviews of relevant literature and patents.
- Producing high quality scientific or engineering papers for publication in quality journals, for client reports and patents.
Location: CSIRO Manufacturing, Clayton, Victoria and Swinburne University of Technology, Hawthorn, Victoria
Salary: $80k to $91k plus up to 15.4% superannuation
Tenure: Specified term of up to 3 years
Ref no: 57054
To be successful you will have:
- A doctorate (or will shortly satisfy the requirements of a PhD) in a relevant discipline area, such as optics, biophysics or bioengineering. Please note: To be eligible for this role you must have no more than 3 years of relevant postdoctoral experience.
- Experience in the development and/or implementation of optical imaging and spectroscopy techniques e.g. FLIM, CARS, OCT and multiphoton imaging in biology, chemistry or physics.
- The ability to develop hardware and software to adapt existing instrumentation to meet project specific needs.
- Demonstrated ability to develop and deliver effective solutions for data analysis and integration.
- High level written and oral communication skills with the ability to represent the research team effectively internally and externally, including at national and international conferences.
- The ability to work effectively as part of a multi-disciplinary, regionally dispersed research team, plus the motivation and discipline to carry out autonomous research.
Before applying please view the full position details and selection criteria here: Position Details document
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We work flexibly at CSIRO, offering a range of options for how, when and where you work. Talk to us about how this role could be flexible for you. Find out more Balance
How to Apply: Please provide a response to the selection criteria for this position to enable the assessment panel to determine your suitability, and upload one document containing your CV/resume, response to each selection criteria and cover letter.
Applications Close: 11:59pm AEST, 19 June 2018.