Postdoctoral Fellow – Visualisation of Genome Structure in Single Cells at EMBL, Heidelberg, Germany

We are seeking for a highly motivated and excellent scientist to join our team. The Ellenberg group is part of the Cell Biology & Biophysics Unit and a multidisciplinary team consisting of biologists, chemists, physicists and computer scientists. Our overall goal is to systematically elucidate the mechanisms underlying cell division (mitosis & meiosis) and nuclear organisation (chromosomes & nuclear pores) with cutting-edge imaging technology. For that purpose, we are developing a broad range of advanced light and electron microscopy technologies to assay the functions of the involved molecular machinery non-invasively, automate the imaging process itself to address as many molecular components as possible, and computationally process image data to extract biochemical and biophysical parameters.

Your role

The successful applicant will apply cutting-edge imaging technologies such as super-resolution microscopy to study the organisation of the genome in 3D in single cells and map its structure to the epigenetic landscape in single cells. S/he will be integrated into our interdisciplinary group and collaborate with several colleagues to advance our knowledge about the 3D folding principles of DNA and their functional consequences in situ in human cells. The successful candidate should be able to work creatively and independently, be well organised, rigorous, and enjoy working in an international team within a highly collaborative atmosphere.

You have

  • PhD in the life sciences or related disciplines.
  • Profound background in molecular cell biology, especially chromatin biology.
  • A competitive CV, also suitable to apply for fellowships if need be.
  • Excellent communication skills and fluency in English are required.

You might also have

  • Experience in advanced light microscopy of single cells.
  • Experience in super-resolution microscopy and/or image data analysis.

Why join us

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collegial and family friendly working environment. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits. Excellent child care facility is available on campus.

What else do I need to know

We are Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1600 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.

Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research.

The working language of the institute is English.

In your online application, you will be asked to include a cover letter, CV and a short (1 page) sketch of a research project you would propose related to visualising 3D genome structure in situ. In addition, please make sure to include contact details of 3 referees in your CV.

Further information about the position can be obtained from the Research Manager of the Ellenberg Lab ( 

Interviews are planned for February 2019.

An initial contract of 2 years will be offered to the successful candidate, however it is foreseen to write a fellowship proposal to acquire additional external funding. Contracts can be extended dependent on funding at the time of contract review.

Location:Heidelberg, Germany

Staff Category:Postdoctoral Fellow

Contract Duration:2 years (extendable)


Closing Date:13 January 2019

Reference Number:HD01433



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