The rising prevalence of obesity worldwide emphasizes the need for improved strategies of prevention and control. Bariatric surgery is currently the most effective treatment of severe obesity and associated diseases, with Roux-en-Y gastric bypass (RYGB) being one of the most often performed procedures worldwide. However, the underlying physiological mechanisms of the surgery are incompletely understood. Candidate mechanisms of RYGB include amplified postprandial gut-hormone response, changes in vagal nerve signaling mediated by intestinal contents and/or gastrointestinal distention, modifications in composition and metabolic activity of gut microbiota , and an altered bile acid physiology and signaling through FXR and TGR5 receptors.
As a result, patients after RYGB often tend to experience earlier satiation, leading to faster meal termination and consequently to smaller meal size. Additionally, changes in food selection after bariatric surgery have been suggested as an important candidate mechanism to potentiate weight loss.
Our research projects are characterized by conceptual and methodological innovation. The candidate will collaborate with transdisciplinary partners from the University of Zurich and international experts in the fields of surgery, neurosciences, endocrinology, gastroenterology, pathology, as well as pharmacology or molecular biology (i.e.: State University of Florida, USA and University College Dublin, Ireland).
The candidate should hold an University diploma in human medicine or an MSc degree in nutritional sciences, psychology, biology, biomedicine, pharmacology, or other relevant fields with excellent qualifications. Designated research and publication experience is desired.
What we offer
The Bariatric Research Group offers a professional, friendly, highly inter-disciplinary, and enthusiastic working environment. Our unit is globally connected and is focused on innovative and dynamic approaches to investigate the behavioral mechanisms underlying changes in food selection and intake in humans with morbid obesity before and after bariatric surgery. The salary will be in the range recommended by the Swiss National Science Foundation.
Place of work
Start of employment
This position is available immediately. Preferred starting date is February/ March 2020 (negotiable) Please submit your application by 31.01.2020.