Postdoctoral studies in structural biochemistry of mitochondrial RNA biogenesis

The Hällberg laboratory is offering a stimulating, interactive international environment. We are part of the Department of Cell and Molecular Biology at the Karolinska Institutet in Stockholm, Sweden, one of the world’s leading medical universities. The lab is located in Biomedicum at the Solna campus of the Karolinska Institutet.

We are seeking a highly motivated and enthusiastic postdoctoral fellow interested in studying the structural cell biology of mitochondrial genome separation and segregation. The project is part of a multi-disciplinary collaboration – financed by the Knut and Alice Wallenberg Foundation – between the groups of Alexey Amunts at Stockholm University and the groups of Joanna Rorbach and Martin Hällberg at the Karolinska Institutet.

Duties

The project aims to structurally and biochemically characterize the ribosomal maturation process. The Hällberg subproject in the collaboration focuses on the very earliest mito-rRNA maturation steps that occur co-transcriptionally and involves the early processing steps and their coordination with binding of ribosomal proteins and maturation factors. Main techniques involved are electron microscopy (cryo-EM), macromolecular crystallography and biochemistry. We have ample access to Karolinska Institutet’s 3D-EM facility that currently features a Krios G3i with a Bioquantum K3, an Aquilos 2 cryo-FIB-SEM, a Leica SP8 cryo-confocal, a Talos 120C G2 and a range of sample-preparation equipment.

Entry requirements

We are looking for highly motivated, independent and driven candidates. The successful applicant will have a background either in structural biology or RNA/RNA-protein biochemistry willing to learn or develop skills in state-of-the-art techniques for studying the structural biochemistry of protein-RNA complexes. A documented ability to independently carry out experimental research projects is required, as are good communication skills in spoken and written English.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location: Solna

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and names with contact information for three references.

The application is to be submitted on the Varbi recruitment system.

Applications will be screened continuously, and we may start the interview process before the last day of application.

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