Postdoctoral and Academic Positions at the Oklahoma Medical Research Foundation, is an independent, nonprofit biomedical research institute, United States
US-OK-Oklahoma City
Post-doctoral Fellow- Vascular & Platelet Biology
Post-doctoral research positions are available in the Xia lab to study vascular and platelet biology using conditional gene knockout mice as models. Seeking self-driven, highly motivated individuals. Willingness to interact with other members of the laboratory in a way that raises the scientific excellence of the whole group. This position will focus on projects that lead to high quality publications. Research backgrounds with mouse models, vascular biology, platelet biology, and glycobiology is preferred but not required.CategoryScientific ID2023-1576 DepartmentCardiovascular Biology – Xia ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow/Assistant Staff Scientist- Cardiovascular Disease
A postdoctoral research position is available in Dr. Jasim Ahamed’s laboratory to study the role of TGF-beta in organ fibrosis and cardiovascular disease (Antioxid Redox Signal. 2021 (PMID: 34619980); AIDS. 2020 Jun 1;34(7):989-1000 (PMID¨32167970); Blood Adv. 2019 Mar 12;3(5):777-788. (PMID: 30846427); Meyer et al. Blood 2012, 119:1064. (PMID:22134166). We are seeking individuals with experience in biochemistry, molecular biology, in vivo mouse models for cardiovascular disease, and ultrasound imaging techniques. CategoryScientific ID2023-1575 DepartmentCardiovascular Biology – Ahamed ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Summer Laboratory Technician
Responsibilities: Perform routine laboratory procedures according to standardized protocols and report results. Receive general instructions on routine work and detailed instructions on new assignments. Receive regular supervision for most assignments. Support team to achieve goals. Expected to perform the following duties after appropriate training and time in the position. Performs routine laboratory procedures according to protocol may include but not limited to DNA extraction, processing blood samples, maintaining cell cultures, isolating RNA, making solutions, buffers, reagents, handling research animals, etc. using standard techniques and/or complex lab equipment. Receives general instructions on routine work and detailed instructions on new assignments. Receives regular supervision for most assignments. Supports team to achieve goals. Expected to perform the following duties after appropriate training and time in the position.CategoryLaboratory ID2023-1572 DepartmentCell Cycle & Cancer Biology – Dawson ClassificationTemporary
Job LocationsUS-OK-Oklahoma City
Animal Support Technician
1. Performs cleaning, sanitization, and preparation of caging and accessories by processing dirty and clean cages and equipment for a variety of laboratory animal species in a timely manner. 2. Operates equipment including autoclaves, mechanical washers, bedding dispenser, per department SOP’s. 3. Perform daily maintenance requirements of equipment as per SOP’s and notify supervisor of any equipment malfunctions. 4. Sanitize all areas of facility per department SOP’s. 5. Maintain quality control records. 6. Observe SOP’s for traffic flow within facility to prevent cross-contamination. 7. Assist with monitoring facility environment, notify supervisor of any problems detected. 8. Receive and store incoming supplies; maintain storage room. 9. Performs all other duties as assigned. General Responsibilities 1. Performs, as directed, safety compliance and uses Personal Protective Equipment (PPE), as needed. 2. Participates in Quality Assessment (QA) and Quality Improvement (QI) programs, as directed. 3. Maintains positive working relationships as a team player through problem solving issues, speaking positively about others, listening attentively and observing the confidentiality of research needs. 4. Increases customer service knowledge, skill and ability by participating in departmental training program. 5. Delivers service that exceeds expectations by problem solving with other employees as appropriate 6. Maintains a clean and safe working environment.CategoryLaboratory ID2023-1571 DepartmentComparative Medicine (LARC) ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Research Technician
The Ocañas Lab is hiring a Research Technician to contribute to projects focused on brain aging and neurodegeneration using in vivo mouse models. Primary responsibilities will include mouse colony management (breeding, genotyping, record keeping), molecular biology techniques (qPCR, sequencing library preparation), and regular lab maintenance tasks. Other skills will be added as needed to support the research program. In-depth training will be provided for all tasks (no advanced experience required).CategoryLaboratory ID2023-1570 DepartmentGenes & Human Disease – Ocañas ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Major Gifts Officer
The Major Gifts Officer (MGO) is a member of the Philanthropy and Community Relations team and is responsible for securing financial resources for OMRF. The primary focus is meeting and working with donors and prospects with significant giving capacity to accomplish their giving objectives in the form of major gifts. The MGO will engage in and be responsible for all aspects of the donor development cycle including donor identification, cultivation, solicitation, acknowledgment, and stewardship. This position reports directly to the Senior Director of Major Gifts and Outreach, under the strategic vision of the Vice President for Philanthropy and Community Relations. Performance Measurements: – Identify major gift prospects. Analyze and predict a donor’s propensity, capacity and enthusiasm to give. – Gather pertinent data to determine the best candidates for the major gifts program. – Cultivate major gift prospects, investing the necessary time and energy to build relationships designed to understand the donor/prospect goals with the expressed purpose of alignment with OMRF’s mission and objectives. – Solicit major gift prospects. Moving prospective major donors along the donor pipeline ready to receive an appropriate ask based upon donor intent and interest. – Stewardship of major gift donors. Develop stewardship strategies that continue the major gift relationship for future gifts and planned giving opportunities. – Manage a portfolio of approximately 150-200 qualified relationships and apply a custom cultivation strategy for each donor. – Collaborate with team members on the creation of content for written communications including proposals, collateral, and stewardship reports. – Prioritize and complete ongoing tasks following established departmental guidelines and policies. – Track prospects and donor contacts in portfolio using organization tools and tracking methods via SalesForce. Experience: – A proven fundraising track record, as well as possible history in finance, sales, and marketing – The ability to lead, work in a team setting, and work independently – Detailed and in-depth knowledge of fundraising, it’s impact and tax-laws associated – Comfort in researching and analyzing large groups of data to uncover prospects – Excellent verbal and written communication aptitude – Capable of handling numerous tasks at once and still meeting deadlines – Demonstrated history of securing major gifts over three or more years CategoryAdministrative ID2023-1569 DepartmentDevelopment ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Multiple Sclerosis Clinical Investigator
The Oklahoma Medical Research Foundation (OMRF) Multiple Sclerosis Center of Excellence is undergoing an exciting time of clinical and clinical research expansion through generous philanthropic support. We are recruiting two physician investigators with clinical research interests in investigator-initiated clinical trials, outcomes research, or other patient-oriented investigation to join our strong multi-disciplinary MS clinical care and research team. Building on strong clinical research infrastructure with longitudinal cohorts, a cadre of talented clinical coordinators/clinical research nurses, diverse aspects of clinical research informatics and a CAP-certified biorepository, we invite qualified candidates to apply for a clinical investigative position focusing on multiple sclerosis and related disorders. We are currently recruiting at the Assistant/Associate/Full Member level (Assistant/Associate/Full Professor equivalent). Talented candidates at all levels are encouraged to apply and will be considered. Successful applicants will: – Spearhead investigator-initiated, sponsor-led and/or NIH clinical trials – Provide comprehensive, optimal, science-driven multiple sclerosis patient care – Receive generous, multi-year start-up package with significant, sustained salary and research support – Collaborate with basic scientists interested in MS patient-oriented translational research – Interact closely with Oklahoma University Health Sciences Center faculty and participate in OUHSC house staff and medical training programs – Contribute toward and enjoy access to: – vibrant patient cohorts with associated patient care and clinical trials infrastructure – extensive autoimmune disease and control bio-specimen collections – outstanding OMRF and ACI Clinical and Research Core facilities Arthritis and Clinical Immunology investigators have access to a number of outstanding OMRF core facilities, including and state-of-the-art clinical facilities. Extensive autoimmune disease and control sample collections are also available. Pilot programs are also available through the Oklahoma Shared Clinical & Translational Resources funding streams, as well as through the Oklahoma Center for Advancement of Science and Technology. Our clinicians provide outpatient care with no in-patient admission or consulting requirements. OMRF (http://omrf.org) is an independent, not-for-profit biomedical research institute adjacent to the University of Oklahoma Health Sciences Center (OUHSC) campus in Oklahoma City. OMRF investigators enjoy close scientific interactions with OUHSC faculty and participate in OUHSC graduate programs. For more information about the OMRF MS Center of excellence, please visit: https://omrf.org/patient-studies/multiple-sclerosis/. For more information about the Arthritis and Clinical Immunology Research program, please visit: https://omrf.org/programs/arthritis-clinical-immunology-research-program/. CategoryScientific ID2023-1568 DepartmentArthritis & Clinical Immunology – Pardo ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow – Immunology
The Montgomery Lab is a translational laboratory focused on understanding the mechanisms of complex diseases known to have genetic underpinnings and immune dysregulation. We have a particular interest in sarcoidosis, a granulomatous disorder that disproportionately affects women and people of African ancestry. We focus to better understand the pathogenesis of disease through immunological characterization and genomic profiling. We have large, complex datasets partnered with detailed clinical data to improve the lives of patients with of immune-mediated diseases. The successful candidate will be part of a dynamic team with synergistic skills and experiences and will be given the opportunity to develop projects that complement the overall directions of the group. The team utilizes high throughput assays, deep phenotyping, single cell genomic, proteomic, and computational and bioinformatics analyses. We also have access to high performance computational resources both in-house and through cloud-based resources. Trainees have the opportunity to participate in large, NIH-funded consortia like TOPMed. This position also allows for cross-training in the data sciences via the OMRF Center for Biomedical Data Sciences for which Dr. Montgomery is the Director. This is a mentored position for postdoctoral training. Individuals at this level plan, design and conduct research experiments; manage research projects; prepare reports and papers for publication, presentation and future research; contribute to grant writing and are encouraged to write applications for fellowships; learn the complexities of research lab management and participate in various lab activities. Benchmark Expectations – Conduct scientific research – Manage research projects – Present scientific information both formally and informally – Prepare papers for publication – Contribute to grant writing – Perform lab responsibilities as assigned – Work collaboratively and collegially as part of the team while developing skills needed as an independent scientist. Knowledge, Skills, and Abilities Knowledge of the principles and practices of scientific theory and research; demonstrates skill in formulating and testing hypotheses; demonstrates ability to conduct scientific research analysis and summarize data and results; writes technical, scientific papers; writes grants and communicates effectively both orally and in writing; mentor students; provides analytic support and input to other projects in the group and guides/directs the work of less senior scientists.CategoryScientific ID2023-1565 DepartmentGenes & Human Disease – Montgomery ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow
The Bodine Lab is seeking a Post-doctoral Fellow. Incumbents at this level will be mentonerd and will plan, design and conduct research experiments; manage research projects; prepare reports and papers for publication, presentation and future research; contribute to grant writing and are encouraged to write applications for fellowships. Learn the complexities of research lab management and participate in various lab management responsibilities.CategoryScientific ID2023-1564 DepartmentAging & Metabolism (A&M) ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Clinical Social Worker
Responsible for professional social work services and assisting multiple sclerosis patients to include identifying medical assistance programs and mobility assistance programs; assisting patients with insurance and prior authorization questions, performing neuropsychological evaluations, counseling patients and/or patient care partners. Serves as an educational resource for patients/families for disease-oriented support. Provides case management services and may give presentations to a variety of audiences. Essential Functions Assessment – Completes comprehensive psychosocial and other appropriate assessments for patients; may interview patients as well as their family members/significant others to gather relevant information; effectively uses professional skills, objectivity and insight to interpret data and to identify viable options. Education & Resources – Gives presentations regarding the autoimmune disease clinic to patient groups, other health care providers, and potentially donors. Assists patients with health related issues acting as their educational resource for disease-oriented support; interprets and explains medical assistance, mobility assistance benefit programs to patients and helps with insurance and prior authorization questions. Counseling & Support Services – Provides case management and counseling services as appropriate; provides advice, guidance, and emotional support and other assistance as needed to patients. Treatment Input & Reporting – Presents regular informal oral presentations of progress and results to the supervisor and colleagues. Maintains the highest standards of ethical behavior. Performs other duties as assigned by supervisor.CategoryAdministrative ID2023-1563 DepartmentArthritis & Clinical Immunology – James ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Full-time or Part-time Research Technician
The Ahamed lab is looking for a full-time or part-time Research Technician. Our laboratory studies mouse models of heart diseases with a particular focus on fibrosis. We utilize state-of-the-art techniques in genetics, molecular biology, cell biology, and biochemistry. The position involves breeding of our mouse colony, performing experiments utilizing a variety of techniques, analyzing data, contributing to management and contributing to laboratory management and oversight. Assists, as needed, with administering injections, medications, venipunctures, applying wound dressings, and with diagnostic procedures as directed by supervisor and/or consulting veterinarian. Identify, prepare and perform a variety of research experiments according to protocol. Projects and assignments are typically non-routine and variable in nature. Receive no instruction on routine work, but receive instructions on new work or special assignments. Collect and present data to Manager or Principal Investigator.CategoryLaboratory ID2023-1562 DepartmentCardiovascular Biology – Ahamed
Job LocationsUS-OK-Oklahoma City
Summer Laboratory Technician
Assist with our development of text-mining software to identify and evaluate statistical discrepancies and other errors within scientific papers. Specific duties will include code development in Python and deploying/testing it on a local web server that uses Flask. Flexible work schedule.CategoryLaboratory ID2023-1561 DepartmentGenes & Human Disease – Wren ClassificationTemporary
Job LocationsUS-OK-Oklahoma City
Research Technician
The Miller lab is currently hiring for a Research Technician who will design, perform and analyze complex research experiments. Organizes, interprets, and communicates data to supervisor and co-workers. Modifies protocols to improve processes. Documents work appropriately. Troubleshoots problems in lab. May provide guidance to research staff, graduate students, and post docs. Collaborates, builds constructive relationships, and effectively communicates with other members of the lab. Works independently, but seeks assistance when needed. Operates highly specialized equipment requiring moderate to high degree of skill. Expected to perform more advanced techniques after appropriate training. Ability to work well with others is essential.CategoryLaboratory ID2023-1560 DepartmentAging & Metabolism – Miller
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow
We are looking for a highly motivated postdoctoral research fellow to join the multidisciplinary Stout Laboratory within the Aging & Metabolism (A&M) Research Program at OMRF. The fellow will investigate how sex hormones and their receptors modulate hypothalamic neurocircuitry and the sex-specific regulation of systemic metabolism during the aging process. The successful candidate will employ a wide range of techniques including stereotaxic injection of AAVs into the brain, chemogenetic approaches (DREADD), brain imaging, single-cell transcriptomics, in vivo metabolic assessments, and a variety of cellular & molecular biology techniques. The candidate will present their data regularly in laboratory meetings, local seminars and symposiums, and will have opportunities to present their work at national conferences. A requirement of the position is that the candidate must demonstrate ethical behavior at all times, a high level of scientific rigor, and must be detail oriented and able to work independently and as part of a team. The Stout Laboratory and A&M Research Program welcome applicants from diverse backgrounds that thrive in a highly collaborative and supportive environment. We are strongly committed to providing individualized mentoring and assistance with career advancement through the implementation of a postdoctoral mentoring committee. The A&M Research Program, which currently consists of 13 highly collaborative investigators, provides an exceptional training environment in aging biology (Geroscience). The A&M Research Program also has a strong collaborative history with faculty from the Oklahoma Center for Geroscience and Health Brain Aging at OUHSC which has resulted in a Geroscience Training Grant (T32 AG052363) that supports graduate students and postdoctoral fellows at OMRF and OUHSC. The collaborative program also houses the Oklahoma Nathan Shock Center of Excellence in Basic Biology of Aging (P30 AG050911), which provides pilot funding for junior investigators. OMRF also offers an annual grant writing course (F-troop) for graduate students and postdoctoral fellows that plan to prepare grant applications (F- or K-awards) for the NIH. The OMRF Postdoctoral Association offers additional training opportunities related to grant writing, presentation skills, and career development. The vibrant and highly collaborative environment within OMRF has resulted in the foundation being named the top large employer in the state of Oklahoma three times in the last five years.CategoryScientific ID2023-1559 DepartmentAging & Metabolism – Stout ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Senior HR Recruiting Specialist/Advisor/Manager
Join a welcoming, passionate, dynamic, diverse, diligent organization and Human Resources team and make a difference! Enjoy ongoing career training and development, and a positive, supportive environment. We seek an ace recruiter to lead the recruiting team and provide a variety of recruitment services. Strategically partner with hiring managers, build applicant pipelines, source candidates, write, post and advertise positions, attend career fairs, screen applicants, conduct interviews, check references, and administer other recruiting assistance while ensuring optimal customer service with a mission-oriented and DEIA mindset, compliance with Equal Employment Opportunity policies and Department of Labor regulations and laws. Develop and assist with the execution of social media, other marketing and proactive recruiting strategies by collaborating with HR, Public Affairs, and others. Assist with the implementation of diversity, equity, inclusion, and accessibility efforts. Generate and analyze AAP data in partnership with our external vendor and help initiate any necessary changes. May assist with oversight and coordination of summer programs. Our future teammate will also help respond to routine and moderately complex HR inquiries with discretion and judgment and may contribute to other HR functions such as onboarding, immigration, employee record keeping and employee relations by collaborating with supervisors and HR team members to provide guidance, solutions, and options. Assist with certain compensation functions to include updating/developing job descriptions and career ladders and helping determine salaries for new hires. Provide project assistance, help coordinate employee functions with other HR team members, and perform other duties as assigned.CategoryAdministrative ID2023-1556 DepartmentHuman Resources
Job LocationsUS-OK-Oklahoma City
Research Technician II/Research Technician III
The Guthridge & James labs are seeking a highly motivated and organized individual to contribute to projects designed to deconstruct the drivers of autoimmune disease at the molecular level in both preclinical and advanced disease states. Studies characterizing the immune cells and their responses against pathogens and autoreactive responses at the cellular and tissue levels using advanced single-cell multiomic phenotyping approaches, high-dimnensional biomarker profiling, and spatial multiomic techniques. Duties will include both basic and advanced cell and molecular biology techniques, such as Luminex and Olink biomarker assays in addition to ELISAs, Western blotting. Single cell techniques including multi-parameter flow cytometry, high-dimensional mass cytometry (CyTOF), imaging mass cytometry (Hyperion), and single cell transcriptomics, proteomics and repertoire using the latest 10X genomics platforms.CategoryLaboratory ID2023-1555 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow- Cardiac Cellular and Mitochondrial Metabolism
The Lee laboratory at the Cardiovascular Biology Research Program (CVB) of OMRF is seeking Postdoctoral Fellows to lead research projects. Our NIH-funded research program (https://leelab.omrf.org/) investigates mechanisms linking mitochondrial and NAD+ metabolism to pathogenesis of cardiometabolic diseases. Fellows will have access to resources and equipment for cardiac physiology and electrophysiology, metabolism, cardiomyocyte and mitochondrial function, proteomics, metabolomics, informatics and spatial transcriptomics from the Lee lab, CVB, CMRO-CoBRE (https://cellularmetabolism-cobre.omrf.org/), OMRF core facilities (https://omrf.org/research-faculty/core-facilities/) and collaborations. Candidates must be self-motivated, proactive and enthusiastic about their research career development. The Principal Investigator (PI) and the postdoctoral mentoring committee will be committed to prepare fellows for an independent research career. Candidates are expected to work independently and contribute intellectually to facilitate a stimulating environment within the research group and among research programs at OMRF. OMRF’s postdoctoral fellow association (https://omrf.org/about-omrf/education-outreach/postdoctoral-programs/postdoc-association/) seeks to enhance the training experience by providing scientific, social interaction opportunities and funds to support attendance at scientific meetings or workshops. Successful candidates will have a recent doctoral degree (within 0-3 years or expect to receive the degree within a year) in cardiovascular physiology, biochemistry or related biomedical disciplines. First-authored publication(s) from the graduate work is expected. Prior research experience and publication(s) investigating cardiometabolic diseases in mouse model are required. Experience in echocardiography, electrophysiology and surgical techniques for heart disease is a plus. CategoryScientific ID2023-1554 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Temporary Scientific Instrument/Facility Technician
Completes required work order forms and follows up on repair orders to ensure maintenance is completed in a timely manner. Performs a variety of duties in the maintenance and repair of buildings and grounds including carpentry, electrical, plumbing, and repair tasks; performs minor troubleshooting, repairs, and adjustments on equipment, appliances, and/or machinery. Exercises discretion in identifying projects requiring the services of a higher skilled crafts person. Assists highly skilled workers involved in the adjustment, maintenance, part replacement and repair of equipment or machinery. Activates and deactivates building alarms and responds to alarm calls during and after regular work hours. Responds to the Foundation emergency telephone/radio and contacts the appropriate authority, i.e., fire department, Foundation security, police department, or contractors. Notifies management of any problems and status of the situation. Maintains a safe work environment by following safety rules and federal regulations. Perform other duties as assigned by supervisor.CategoryAdministrative ID2023-1553 DepartmentFacility Services
Job LocationsUS-OK-Oklahoma City
Administrative Assistant II/III/IV
Provide assistance and organization to multiple Principle Investigators (PIs) in the Arthritis and Clinical Immunology Research Program. Update and organize CVs and Biosketches for PIs. Assist in organizing bibliographies and published paper collections, monitoring for Public Access compliance. Assist in drafting and/or editing letters, regulatory documents such as IRB or IACUC applications. Organize and maintain records of grant effort distribution and monthly accounting reports. Monitor and notify PIs of various deadlines well in advance of due date for grant reporting and renewal, membership renewal, abstract, and meeting deadlines. Manage PI calendars. Gather timesheets and get PI signatures. Manage travel arrangements and reimbursements. Assist with purchasing office equipment and supplies. Assist with planning and arranging all aspects of visits for guest speakers, meetings, seminars, and symposia as required for department and PIs. Meet with PIs as needed to review and coordinate workloads, deadlines, etc., and provide feedback regarding completion of major tasks, office operations and any issues. Requesting or pulling publications. Must have a helpful orientation and positive attitude. Filing, copying, picking up/delivering mail, and other administrative tasks. Opportunities to learn grant and manuscript preparation and submission skills. Assists in the preparation of budgets; responsible for maintaining budgetary records and expenditures and other support items for federal grant applications. Edits scientific documents for grammar flow and clarity; ensures compliance with federal grant submission requirements.CategoryAdministrative ID2023-1550 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Research Tech- Biorepository
The Guthridge Lab is seeking a Research Technician for the Biorepository which supports our clinical and translational research investigators. Candidates should be highly organized, motivated and team oriented. Duties will include all repository activities related to receipt, processing, storage, maintenance and records management of human blood and tissue samples related to studies and clinical trials in a CAP (College of American Pathologists) certified facility. Individual will need to be comfortable working in cold temperatures with appropriate personal safety protections and working with human samples.CategoryLaboratory ID2023-1548 ClassificationOn-going
US-OK-Oklahoma City
Assistant/Associate/Full Member(Assistant/Associate/Full Professor Equivalent)
The Oklahoma Medical Research Foundation (https://omrf.org/) is seeking accomplished or upcoming investigators with expertise in aging as it relates to neuroinflammation and/or neurodegeneration to join the Aging and Metabolism Research Program. Successful candidates will be expected to maintain a vigorous independent research laboratory investigating mechanisms relevant to CNS aging associated with one or more of the following areas of special interest: inflammatory processes, circuits relevant to cognition/behavior, immune cell function, and bioenergetics. Successful candidates will receive an appointment at the Assistant, Associate, or Full Member level (Assistant, Associate, and Full Professor equivalents), dedicated research space, as well as a generous, multi-year start-up package with significant sustained salary and research support. The Aging and Metabolism Research Program is comprised of thirteen faculty members studying a variety of diseases related to the aging process, including neurological, metabolic, musculoskeletal, and cardiovascular disorders. OMRF supports an AAALAC accredited animal facility as well as state-of-the art core facilities for imaging, -omics technologies, tissue banking, and other facilitating resources. Additional information can be found at the Program’s website (http://omrf.org/programs/aging-and-metabolism-research-program/). Other attractive aspects include a generous startup package, institutional support for competitive salaries, comprehensive benefits, and a collegial work environment. OMRF investigators have no formal teaching obligations but can voluntarily participate in didactic activities on campus at The University of Oklahoma Health Sciences Center (OUHSC). Overall, OMRF is committed to creating an attractive position suitable for applicants with a proven track record or exceptional potential for high-quality funded research. OMRF is an independent, not-for-profit, biomedical research institute supporting five major interdisciplinary research programs. Our facilities are located adjacent to the campus of the University of Oklahoma Health Sciences Center (OUHSC) and the Oklahoma City VA Medical Center near downtown Oklahoma City. OMRF investigators are integral participants in OUHSC graduate programs and enjoy close scientific interactions with OUHSC and Oklahoma City VA faculty. EOE/AA Employer/Vet/DisabledCategoryScientific ID2023-1546 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow
The Rankin Lab is seeking a Post-doctoral Fellow to study chromosome assembly and dynamics, how these events are controlled, and how corruption of these processes contributes to disease. Our lab forms part of the Program in Cell Cycle and Cancer Biology, which offers an excellent training environment in a state-of-the-art facility. We use a variety of experimental models, including cultured cells, biochemistry, extracts from frog eggs, and advanced microscopy to address problems of chromosome structure, replication, and inheritance. Experience directly related to this field is not necessary, but basic molecular biology skills are preferred. Applicants should demonstrate enthusiasm for the topic, willingness to learn, and the ability to work independently to develop their project(s), analyze experiments, and prepare manuscripts. Successful candidates will have good written and verbal communication skills and be willing to engage fully in lab and departmental activities. During their tenure in the Rankin lab, fellows will receive significant career development support. They can also expect to attend training courses as well as scientific conferences, where they can present their work and establish their presence in the research community.CategoryScientific ID2023-1545
Job LocationsUS-OK-Oklahoma City
Research Technician/Research Technician II
The Yu Lab is currently hiring for a Research Technician to assist with research activities directed toward understanding the roles of cellular metabolism in vascular development and disease. Basic duties will include working with laboratory mice, PCR genotyping, reagent preparation, ordering supplies, and general laboratory maintenance and organization. Additional responsibilities will include molecular and cellular biology and histology.CategoryLaboratory ID2023-1542 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Research Technician/ Research Technician II
Job Summary/Basic Function The Lee laboratory investigates mechanisms of heart diseases using mouse models and molecular techniques. The duties of this position will involve mouse handling (managing mouse colony, ear tagging, injections, blood and tissue sample collection, histology, surgical procedures after proper training), molecular biology techniques (PCR genotyping, quantifications of RNA and protein), reagent preparation, supplies ordering, general laboratory maintenance and organization, and data collection and presentation to the Principal Investigator. Assignments are typically non-routine and variable in nature.CategoryLaboratory ID2023-1540 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Project Coordinator/Business Manager
The Arthritis & Clinical Immunology Research Program is currently hiring for a Project Coordinator/Laboratory Business Administrator. Oversee the business, purchasing, and accounting for large research groups. Manage various NIH and industry-funded projects by helping set, assess, and measure progress and milestones; monitor progress, track expenses, coordinate multi-investigator activity and ensure compliance with large, complex collaborative NIH grants and investigator-initiated trials; help track and ensure completion, report generation, billing accuracy for various COBRE, ORDRCC, ACE, AMP, NARCH, OSCTR and other multi-investigator and core efforts. Develop, implement and review business plans for ACI scientific and clinical support cores and marketing strategies to improve broad recognition and use of cores and services. Help establish policies and SOPs for select activities and assist with improving efficiencies and streamlining processes. Help with regulatory paperwork for College of American Pathologist certification of the OMRF Biorepository. Interface with OMRF IRB and Technology Ventures to execute MTAs, service agreements and CDAs. Serve as a Marketplace super-user for the labs, negotiating discounts, placing orders, tracking orders/shipments, and keeping an inventory. Provide justifications as requested. Submit invoices to OMRF Accounting for trial expenses. Track preventive maintenances for equipment. Generate quotes for proposed services and submit, track, retain and collect from invoices for core services. Help set and revise fee structures, provide invoicing information and ensure payment for completed activities. Provide at least monthly updates on all account balances and assist with personnel distribution. Review department budgets to identify cost-saving strategies and appropriate spending. Assist with generating budgets and future projections for lab finances. Update content on lab websites. Perform technical and scientific writing for reports and grant applications.CategoryAdministrative ID2023-1533
Job LocationsUS-OK-Oklahoma City
Executive Administrative Assistant to VP of Clinical Affairs
Provide assistance and organization to VP, multiple Principal Investigators (PIs) and staff. Maintain a professional office environment at all times. Manage all calendars, scheduling meetings, sending reminders, and arranging zoom meetings or teleconferencing. Answer multiple phone lines, take messages, and convey them to VP and PIs as necessary. Collect leave requests and timesheets monthly for over 160 employees to check for accuracy, supervisor signatures, etc., for submission to Payroll. Maintain files. Monitor and notify staff, PIs and VP of various deadlines well in advance of due date, especially for membership renewal, abstract, and meeting deadlines. Manage all travel arrangements and reimbursements then coordinate with accounting as needed. Assist organizing PI offices. Assist purchasing office equipment and supplies. Update and organize CVs. Assist with organizing bibliographies and paper collections. Maintain instructions for journal and grant submissions. Assist with letters of support for grants, promotions, applications, etc. Assist with copy editing, graphic preparation, on-line submissions and review that publication or grant submissions meet the requirements of specific journals or granting agencies. Assist with IRB applications and other regulatory documents, as needed. Assist with credentialing for medical organizations, insurance, licensure, and board certification. Organize and maintain records of grant effort distribution. Be able to multi-task and prioritize tasks, while maintaining a positive work orientation.CategoryAdministrative ID2023-1532
Job LocationsUS-OK-Oklahoma City
Research Technician
The Van Remmen Lab is looking for a Research Technician or Senior Research Technician to conduct basic research in aging, skeletal muscle biology and mitochondrial function through in vitro and in vivo approaches with mice. Specific duties include, but are not limited to mammalian cell culture, western blotting, real time PCR analysis, basic biochemical assays, immunohistochemistry, mouse handling, euthanasia and dissection, and PCR genotyping.CategoryLaboratory ID2023-1528 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Research Technician II/ Research Technician III
Performs laboratory procedures according to standardized protocols and reports results. Receives regular supervision for most assignments. Experience with aseptic techniques is preferred and prior experience in basic immunology protocols such as flow cytometry, ELISA, Western blots, and/or immunohistochemistry is highly desired. Individual will need to be comfortable working with human samples and is expected to perform routine work with minimal supervision after appropriate training and time in the position. Responsibilities will include: – maintains lab inventory, prepares common lab buffers, and re-order supplies as needed – maintains donor database and organizes blood collections, either on site or through the Rheumatology Clinic – processes blood samples and performs basic research protocols (flow cytometry, ELISA, Western blots, etc.) – prepares written reports and/or presents work at lab meetingsCategoryLaboratory ID2023-1519 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Assistant Staff Scientist
The Finn Lab at OMRF is looking for an innovative, dedicated scientist for a full-time staff scientist position. We study how variability in genome organization can give rise to cellular phenotypes. You will be trained in techniques specific to the lab. You will bring your own expertise. Together, we’ll develop an exciting, independent research project that you will oversee and manage. As the work develops, there will be opportunities for mentorship of students, publication, and formal and informal presentations. Benchmark Accountabilities: • Independently conducts scientific research • Oversees and/or manages a research project • Mentors more junior lab members • Shares in regular lab maintenance tasks • Assists with grant writing and writing papers for publication • Presents scientific information both formally and informally Knowledge, Skills, and Abilities: • Knowledge of the principles and practices of scientific theory and research • Skill in formulating and testing hypotheses • Verbal and written communication skills • Ability to design and conduct scientific research experiments • Ability to analyze and summarize data and results • Ability to write scientific papers and grants • Ability to mentor students and guide the work of less senior scientistsCategoryScientific ID2022-1503 DepartmentCell Cycle & Cancer Biology – Finn
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow
The Finn Lab at OMRF is looking for excellent candidates for a position at the level of postdoctoral research fellow. We study how variability in genome organization can give rise to cellular phenotypes. You will be trained in techniques specific to the lab. You will bring your own expertise. Together, we’ll develop an exciting, independent research project that you will oversee and manage. As the work develops, there will be opportunities for grant-writing, mentorship of students, publication, and formal and informal presentations. The eventual goal is to help you build the independence you need to advance your career. Benchmark Accountabilities: • Independently conducts scientific research • Oversees and/or manages a research project • Mentors more junior lab members • Shares in regular lab maintenance tasks • Assists with grant writing and writing papers for publication • Apply for training grants and other funding if eligible with assistance and guidance • Presents scientific information both formally and informally Knowledge, Skills, and Abilities: • Knowledge of the principles and practices of scientific theory and research • Skill in formulating and testing hypotheses • Verbal and written communication skills • Ability to design and conduct scientific research experiments • Ability to analyze and summarize data and results • Ability to write scientific papers and grants • Ability to mentor students and guide the work of less senior scientistsCategoryScientific ID2022-1502 DepartmentCell Cycle & Cancer Biology – Finn
Job LocationsUS-OK-Oklahoma City
Clinical Research Nurse
Coordinates and executes rheumatology research projects. Performs nursing duties in a rheumatology research clinic setting including research and data management, patient care, sample collection and processing, and medication administration. Tasks require a high level of organizational skills and the ability to ask the right questions to determine proper course of action while following established standards and research protocols. DUTIES: 1. Clinical Trials. Conducts research and assists researchers by recruiting patients, determining eligibility for clinical trials, and seeing patients through research studies including obtaining informed consent, administering questionnaires, taking medical histories, study drug administration, assessing and reporting adverse events, and performing all study related tasks as outlined in study protocols and in adherence with GCP, ICH, and HIPAA regulations. 2. Chart Review. Performs medical chart review to abstract data for research including but not limited to constructing medical history and medications chronology, evaluating disease progression, and mapping symptom and biomarker associations. 3. Communication. Liaises between principal investigator, patients, third party patient care service providers, research sponsors, and governing agencies to ensure strict adherence to protocol and regulations throughout study conduct. Excellent written and oral communications required. 4. Patient Care. Assesses and records symptoms, vital signs, and other patient information required for research protocols and to prepare patient for examination. Review records for documentation of study inclusion/exclusion criteria. Carries out physician orders for testing and treatment and coordinates follow-up care of patients. 5. Sample Collection. Collects samples from patients including blood, urine, saliva, etc. Prepares samples for analysis or shipment. Collects all laboratory reports, data, and records. Excellent phlebotomy skills required. 6. Medication Administration. Under direction of physician or other medical personnel, administers FDA approved and investigational medications to patients. IV certification preferred. 7. Data Management. Gathers, organizes, analyzes, and submits patient and research data to principal investigators, scientists, and sponsors. Computer skills required. 8. As Needed. Performs various duties as needed to successfully fulfill the function of the position.CategoryOther ID2022-1481
Job LocationsUS-OK-Oklahoma City
Assistant Member (Assistant Professor equivalent)
The Genes and Human Disease Research Program at the Oklahoma Medical Research Foundation (omrf.org) invites candidates to apply for an investigator position at the Assistant Member level (Assistant Professor equivalent). Current investigators in GHD study questions related to human disease through both model organism and human studies. Our expertise varies from stem cell biology, genome editing, genomics bioinformatics, and neuroepigenetics to human health-related problems including autoimmune diseases, aging, hearing loss, and regeneration. We seek to identify a candidate who will establish an independent research career as well as catalyze collaborative research in our highly interactive program. All investigators at OMRF have access to state-of-the-art core facilities, including an Imaging Core, animal facilities, and modern, next generation sequencing technology and bioinformatics platforms. The successful candidate will receive a generous, multi-year, start-up package with significant salary, equipment, and research funding. OMRF also provides substantial ongoing salary support and research support after the start-up period has ended. OMRF is an independent, not-for-profit biomedical research institute adjacent to the campus of the University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City. Oklahoma City offers a dynamic and burgeoning midtown area near the campus, and a very reasonable cost of living. We are committed to addressing additional needs of faculty, including dual career couples and single parents. We are particularly focused on overcoming barriers to gender equity in science. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status, or any other legally protected characteristic.CategoryScientific ID2022-1461 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Research Technician / Research Technician II
The Van Remmen lab is looking for a Research Technician/Research Technician II to conduct basic research in aging, skeletal muscle biology and mitochondrial function primarily through in vitro cell culture techniques. Specific duties include, but are not limited to cell culture, western blotting, real time PCR analysis, and basic biochemical assays.CategoryLaboratory ID2022-1460 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Program Manager
The James lab is looking for a Program Manager to assist with the leadership and program management of national, high-visibility NIH & Industry funded project portfolio focused on clinical-and translational research programs across multiple autoimmune diseases including lupus, rheumatoid arthritis, Sjogren’s syndrome and psoriatic spectrum diseases. The successful applicant will be an organized, high-energy project manager at the center of the administrative management of multiple NIH and industry funded projects to include the following responsibilities: 1) draft and implement program policies and procedures 2) help set, assess and report on program progress and milestones 3) coordinate overall program budget allocations between subproject sites and funding organizations 4) coordinate and document proceedings of the program steering committee, leadership and subproject committee meetings 5) ensure all parties of programs are in compliance with all regulatory obligations including material transfer agreements, human subjects research training, and institutional review board protocol approvals 5) assist with the logistics and compliance of clinical operations and sample processing training 6) monitor deadlines and deliverables helping to re-aliquot resources and ensure all parties are meeting and exceeding expectations, 7) assembling slide presentations to highlight progress and emphasize areas needing additional help, 8) helping monitor and document publications, presentations and summary documents. In addition, this position will also engage in management of other divisional activities for multiple investigators, collaborative NIH grants, and investigator-initiated clinical trials. Such management activities include but are not limited to establishing policies and SOPs for select divisional areas and assist with improving efficiencies and streamlining processes, verification of billing and expenses across lab/divisional multi-investigator projects, technical and scientific writing for reports and grant applications, marketing of clinical resources and technology core capabilities to attract investments by BioPharma in Arthritis & Clinical Immunology opportunities.CategoryAdministrative ID2022-1454 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Administrative Assistant / Administrative Assistant II
Provide assistance and organization to multiple Principle Investigators (PIs) in the Arthritis and Clinical Immunology Research Program. Update and organize CVs and Biosketches for PIs. Assist in organizing bibliographies and published paper collections, monitoring for Public Access compliance. Assist in drafting and/or editing letters, regulatory documents such as IRB or IACUC applications. Organize and maintain records of grant effort distribution and monthly accounting reports. Monitor and notify PIs of various deadlines well in advance of due date for grant reporting and renewal, membership renewal, abstract, and meeting deadlines. Manage PI calendars. Gather timesheets and get PI signatures. Manage travel arrangements and reimbursements. Assist with purchasing office equipment and supplies. Assist with planning and arranging all aspects of visits for guest speakers, meetings, seminars, and symposia as required for department and PIs. Meet with PIs as needed to review and coordinate workloads, deadlines, etc., and provide feedback regarding completion of major tasks, office operations and any issues. Requesting or pulling publications. Must have a helpful orientation and positive attitude. Filing, copying, picking up/delivering mail, and other administrative tasks. Opportunities to learn grant and manuscript preparation and submission skills.CategoryAdministrative ID2022-1453 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Research Technician / Research Technician II / Research Technician III
The Yoon Lab is looking for a highly motivated, organized, responsible person who will play a key role in achieving the mission of the lab. Using Drosophila (fruit fly), we aim to discover cellular and molecular mechanisms how metabolic dysfunctions cause human diseases including neurological diseases. We utilize variety of approaches including genetics, metabolomics, biochemistry, cell and molecular biology as well as confocal and electron microscopy. Responsibilities will include: – Maintenance of Drosophila stocks – Conducting genetic experiments to assess gene function in Drosophila – Prep of Drosophila tissue samples and imaging using fluorescent and confocal microscopes – Conducting basic molecular biology experiments such as PCR and cloning – Detailed documentation of experiments and results – Participation in lab and departmental meetingsCategoryLaboratory ID2022-1452 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Research Technician / Research Technician II / Research Technician III / Research Technician IV
The Kinter laboratory in the Aging and Metabolism Research Program is seeking a Research Technician. The Kinter laboratory has two parts; a proteomics laboratory that helps other scientists use LC-MS in their experiments and an independent research program studying the effects of high fat diets on the heart. The Research Technician will perform routine laboratory procedures according to our laboratory protocols, including but not limited to handling mice, maintaining cell cultures, isolating protein and RNA, gel electrophoresis, Western blotting, and LC-mass spectrometry. They will receive general instructions on routine work and detailed instructions on new assignments.CategoryLaboratory ID2022-1450 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow – Drosophila genetics & neurodevelopmental diseases
The Yoon Lab is looking for a highly motivated, creative, and responsible scientists who will play a key role in achieving the mission of the lab. We aim to discover cellular and molecular mechanisms of Mendelian mitochondrial diseases. To do this, we implement an experimental pipeline that leverages the combined power of clinical data, genomics analysis, and studies using Drosophila models and patient-derived stem cell models. We have discovered 5 new Mendelian mitochondrial diseases including the Harel-Yoon syndrome that bears my name. We have established disease models in Drosophila and human iPS cells. Hence, the motivated postdoctoral researchers are expected to discover new findings and publish high-impact papers. Researchers with strong interest in neurological and mitochondrial diseases are welcome to apply. Expertise in any of the following areas is highly valued though not required: – Drosophila genetics – Metabolism/mitochondrial biology – Neurodegeneration & Neurodevelopmental diseases – Developmental biology – iPSCs/cerebral organoidsCategoryScientific ID2022-1442 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Scientific Medical Writer
The James/Guthridge labs (james.omrf.org; Guthridge.omrf.org) is a translational immunology laboratory focused on understanding the pathogenesis, prediction, prevention and precision treatment of immune-mediated diseases to improve patients’ lives. We have large, complex experimental datasets partnered with detailed clinical data to help better understand disease and improve treatments. We also help lead large, national, NIH funded consortia such as the Autoimmune Centers of Excellence and Accelerating Medicines Partnership in Autoimmune and Immune-Mediated Disease. We are looking for a talented Scientific/Medical Writer to join our team. The Scientific Writer is responsible for producing and/or editing accurate, clear, and interesting content for manuscripts, grants, reports, lay summaries, white papers, website content and presentations. The successful candidate will perform some combination of the following. Apply scientific principles and biomedical knowledge to understand, organize, and describe complex data for scientific, medical, and lay audiences. Coordinate input from a multi-disciplinary team while meeting tight deadlines. Help write, edit and proofread key documents. Maintain familiarity with relevant research, conduct literature reviews, and manage references. Assist with the design, development, and selection of scientific illustrations, tables, and figures. Track manuscript status from conceptualization through publication. Assist with cover letters and associated documents. Assist with letters of support, evaluation letters and other aspects of communication like patient newsletters. Update lab and departmental websites, including newsworthy content. Maintain common-use text describing facilities, resources, human subject sections and standard procedures. Assist with editing and writing grant progress reports, grant sections and collaborative grant documents. Summarize research results for lay audiences and community stakeholders. A senior candidate may assume a leadership role for a Scientific Writing Unit, hosting scientific writing workshops, writing groups and lunch-and-learns for junior investigators and trainees.CategoryAdministrative ID2022-1439 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow – Immunology
The James/Guthridge labs (james.omrf.org; Guthridge.omrf.org) is a translational immunology laboratory focused on understanding the pathogenesis, prediction, prevention and precision treatment of immune-mediated diseases to improve patients’ lives. We have large, complex experimental datasets partnered with detailed clinical data to help better understand disease and improve treatments. Join our dynamic team in a well-funded research group in an autoimmune disease center of excellence. We are focused on identifying and characterizing mechanisms of autoimmune disease onset and flare, including regulatory immune mechanisms. Drs. Joel Guthridge (Guthridge.omrf.org) and Judith James (james.omrf.org) are seeking two Post-Doctoral Fellows with a strong immunology background to be part of the team working to understand mechanisms of autoimmune disease in humans by leveraging the extensive resources and data available from our well characterized clinical cohorts. The successful candidate will be part of a dynamic team with synergistic skills and experiences and will be given the opportunity to develop projects that complement the overall directions of the group. The team utilizes high throughput bimolecular assays, deep cellular phenotyping, single cell genomic, proteomic, chromatin conformation/epigenetic and computational and bioinformatics analyses through resources in our Human Phenotyping and Translational Informatics Cores which are supported through NIH P30 U54 and U19 mechanisms. We also have access to high performance computational resources both in-house and through cloud-based resources. Trainees have the opportunity to participate in large, national NIH-funded consortia. This is a mentored position for postdoctoral training. Individuals at this level plan, design and conduct research experiments; manage research projects; prepare reports and papers for publication, presentation and future research; contribute to grant writing and are encouraged to write applications for fellowships; learn the complexities of research lab management and participate in various lab activities. Benchmark Expectations: – Conduct scientific research – Manage research projects – Present scientific information both formally and informally – Prepare papers for publication – Contribute to grant writing – Perform lab responsibilities as assigned – Work collaboratively and collegially as part of the team while developing skills needed as an independent scientist. Knowledge, Skills, and Abilities: Knowledge of the principles and practices of scientific theory and research; demonstrates skill in formulating and testing hypotheses; demonstrates ability to conduct scientific research analysis and summarize data and results; writes technical, scientific papers; writes grants and communicates effectively both orally and in writing; mentor students; provides analytic support and input to other projects in the group and guides/directs the work of less senior scientists.CategoryScientific ID2022-1437 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow – Bioinformatics
Join our dynamic, well-funded research group in an autoimmune disease center of excellence. We are focused on studying immune mechanisms associated with autoimmunity and translational research questions. Dr. Joel Guthridge and Dr. Judith James are seeking a Post-Doctoral Fellow with a strong immunology and/or bioinformatics/data science background to be part of the team working to apply precision medicine and molecular phenotype classification approaches to clinical and translational autoimmune disease research to improve the lives to patients with autoimmune disease. Large datasets for analysis are already available and growing daily. The successful candidate will help lead efforts to apply computational and new statistical tools to molecular phenotype pipelines for patient characterization and stratification, assist with data analysis, modeling, visualization and interpretation of clinical and experimental data. We have access to an extensive curated electronic clinical research health record and experimental data warehouse already available to be leveraged for these projects. The team utilizes high throughput bimolecular assays, deep cellular phenotyping, and single cell genomic and proteomic methods through our Human Phenotyping Core. We also have access to high performance computational resources both in-house and through cloud-based resources. This is a mentored position for postdoctoral training. Incumbents at this level plan, design and conduct analysis plans for research projects; prepare reports and papers for publication, presentation and future research; contribute to grant writing and are encouraged to write applications for fellowships. Successful candidates will learn the complexities of data analytics/research lab management and participate in various lab management responsibilities. Benchmark Expectations: – Conduct scientific research/data analysis – Manage research projects – Contribute to grant writing; prepare reports and papers for publication – Present scientific/technical information both formally and informally – Work collaboratively and collegially as part of the team while learning to become an independent investigator. Knowledge, Skills, and Abilities: Knowledge of the principles and practices of scientific theory and research; demonstrates skill in formulating and testing hypotheses; demonstrates ability to conduct scientific research analysis and summarize data and results; writes technical, scientific papers; writes grants and communicates effectively both orally and in writing; mentor students; provides analytic support and input to other projects in the group and guides/directs the work of less senior.CategoryScientific ID2022-1436 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Biostatistician / Data Analyst
The James/Guthridge labs (james.omrf.org; Guthridge.omrf.org) is a translational immunology laboratory focused on understanding the pathogenesis, prediction, prevention and precision treatment of immune-mediated diseases to improve patients’ lives. We have large, complex experimental datasets partnered with detailed clinical data to help better understand disease and improve treatments. We are looking for a Biostatistician or experienced Data Analyst to join our team to help analyze current and emerging data. This person will perform biostatistic analyses of clinical trial and associated experimental data. Develops data analysis plans, including power calculations. Performs a wide variety of analyses, including but not limited to parametric and non-parametric statistics. Evaluates the statistical methods and procedures used to obtain data and to ensure validity, applicability, efficiency, accuracy, reliability and usability of data. Reports results of statistical analyses, including information in the form of graphs, charts, and tables. Conveys results for presentations to non-statistical audiences. Analyzes and interprets statistical data and prepares conclusions. Identifies relationships and trends in data, as well as any factors that could affect the results of research. Assists scientists in designing experiments to facilitate correct analysis of data. Plans data collection methods for specific projects and determines the types and sizes of sample groups to be used. Queries databases and manages datasets.CategoryScientific ID2022-1435 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Research Technician / Research Technician II
The Farris and Lessard labs are seeking a highly organized, motivated individual to contribute to projects investigating inflammation and autoimmunity. Duties will include performance of detailed molecular protocols, molecular cloning, quantitative RT-PCR, basic cell culture, ELISA assays, and organization of data into tabular and graphical forms. CategoryLaboratory ID2022-1392 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow – Cellular Metabolism
The laboratory of Dr. Pengchun Yu in the Cardiovascular Biology Research Program at the Oklahoma Medical Research Foundation (OMRF) is seeking postdoctoral scientists. We focus on the interface between cellular metabolism and vascular biology and have a proven track record in this field (Circulation Research, 2010; Circulation, 2012; Nature, 2017; J. Biol. Chem., 2021). More information about the lab can be found at https://yulab.omrf.org/. The successful candidates will work on research projects that study the crosstalk between metabolic programs and angiogenic signaling and the involvement of cellular metabolism in the pathogenesis of vascular diseases. Multidisciplinary strategies will be used, ranging from novel genetically modified mouse models to cutting-edge systems biology tools including metabolomics and single-cell transcriptome analysis. OMRF is an independent, nonprofit biomedical research institute. The innovative basic and translational research at OMRF covers several critical areas such as cardiovascular disease, autoimmune disease, and cancer. OMRF has made The Scientist magazine’s annual list of the “Best Places to Work for Postdocs” for many years. The institute offers postdoctoral fellows an exceptional research and training environment with state-of-the-art facilities and outstanding core technology laboratories including imaging, next-generation sequencing, and clinical genomics. Moreover, postdoctoral scientists are encouraged to apply for OMRF Postdoc Travel Awards to support their attendance at meetings or workshops.CategoryScientific ID2022-1373 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow – Analyst Bioinformatics
The Lessard lab is seeking a Post-doctoral Fellow with experience in computational sciences to join our research team. Our research investigates the regulatory functions that control gene expression within the complex landscape of the three-dimensional genome and how genetic variations influence these regulatory functions to cause human diseases such as Sjögren’s syndrome, systemic lupus erythematosus (SLE), and other autoimmune diseases. We perform a wide variety of high-throughput sequencing technologies in both bulk and single cell technologies: genotyping arrays, RNA-seq, single cell (sc)RNA-seq, Perturb-seq, long sequence Nanopore sequencing, spatial transcriptomics, etc. In addition, we leverage gene-editing technologies, i.e. CRISPR/Cas9 editing, to functionally characterize non-coding regulatory regions of the genome in the context of native 3D chromatin regulatory network using 3C technologies (3C-qPCR, etc.) and promoter capture Micro-C. Candidate must demonstrate proficiency in computer programming (UNIX-like OS, R, and python), and the application of statistical methods commonly used to analyze genetic data. Experience using data analysis pipelines and machine learning analytical approaches is a also preferred. Candidates must also demonstrate an ability to interpret and summarize research findings, and interest in assisting manuscript preparation and grant writing, and presenting at scientific meetings.CategoryScientific ID2022-1364 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Clinical Trials Program Manager
The James Lab and Guthridge Lab are hiring for a Project Manager. This position will help with the leadership of a national, high-visibility NIH & Industry funded projects focused on clinical-translational research programs across multiple autoimmune disease including lupus, rheumatoid arthritis, Sjogren’s syndrome and psoriatic spectrum diseases. The successful applicant will be a dynamic leader at the center of the administrative management of multiple NIH and industry funded projects to include the following responsibilities a.) drafting and implementation of program policies, procedures, b.) helping set, assess and report on program progress and milestones, c.) coordinate overall program budget allocations between subproject sites and funding organizations, d.) coordinate & document proceedings of the program steering committee, leadership and subproject committee meetings, e.) ensure all parties of program are in compliance with all regulatory obligations including material transfer agreements, human subjects and institutional review board protocol approvals, f.) assist with the logistics and compliance with clinical operations and sample processing training, proficiency and performance assessments of national clinical sites. In addition, this position will also engage in management activities of other divisional activities for multiple investigator, collaborative NIH granges and investigator-initiated clinical trials, progress reports, verification of billing and expenses across all lab/divisional projects, marketing of clinical resources and technology core capabilities to attract investments by BioPharma in the unique Arthritis & Clinical Immunology opportunities.CategoryAdministrative ID2022-1356 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow / Assistant Staff Scientist – Lupus
The Nath Lab is seeking a highly motivated, hardworking and organized team player (Post-doctoral Fellow / Assistant Staff Scientist) to join our effort to understand genetic mechanisms of lupus, an autoimmune disease. Using whole genome search, our lab has identified several genes/genetic variants, associated with lupus susceptibility. Now we are trying to understand the specific functional effects of those lupus associated genetic variants, using cell lines, patients-derived primary immune cells or tissues. We will apply various modern techniques for studying features of three-dimensional (3D) genomic organization such as 3C, Hi-C, ChIP-Seq, and genome editing using CRISPR/Cas9. Candidate will be involved in the analysis of human genetic data and the development of computational methods, which requires a mix of computational skills, statistical knowledge, creativity and biological insight. Specifically, candidate will identify novel therapeutic targets and biomarkers from the investigation of human genetic variation (GWAS, Next Gen Sequencing) with disease status and intermediate variables using cutting-edge techniques in Statistical Genetics. Candidate will develop and apply methods for the integration of GWAS summary results with other types of data e.g. eQTL, mQTL, functional genomic annotations, gene networks, estimation/partitioning of heritability, Mendelian Randomization to understand causal direction, and fine mapping. Candidate will collaborate with experimental and clinical scientists to address target mechanism specific questions and seek to support investment decision making with genomic insights.CategoryScientific ID2021-1058 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Post-doctoral Fellow / Assistant Staff Scientist – Genetics of Lupus
The Nath laboratory in the Arthritis and Clinical Immunology research program is seeking a highly motivated, self-starter staff-scientist/post-doctoral level with the ability to work with optimal resources and little direct supervision to address important questions in the genetics and genomics of the systemic lupus erythematosus, an autoimmune diseases. Successful candidates will be proficient in wide range of contemporary molecular biology techniques such as, high-throughput sequencing of DNA, RNA, and methylation, ChIP-Seq, ChIP-qPCR, Single cell genomics, flow cytometry, cloning, cell culture etc. Experience in genome CRISPR/Cas9 or similar approaches will get preference. Competitive individuals will also have some experience in the analysis of genetic data, high-throughput sequencing data and the use of bioinformatics software.CategoryScientific ID2021-1057 ClassificationOn-going
Job LocationsUS-OK-Oklahoma City
Data Analyst / Bioinformatics Specialist
The Nath laboratory is seeking a highly motivated, self-starter senior level scientist with the ability to work with optimal resources and little direct supervision to address important questions in the genetics and genomics of systemic lupus erythematosus (SLE or lupus), an autoimmune disease. Using large-scale genome wise association studies (GWAS), our lab has identified several genes/genetic variants associated with lupus susceptibility. Now we are trying to understand the specific functional effects of those lupus associated genetic variants, using cell lines from patient-derived primary immune cells or tissues. We will apply various modern techniques for studying features of three-dimensional (3D) genomic organization such as 3C, Hi-C, ChIP-Seq, RNA-seq and genome editing using CRISPR/Cas9 based techniques. Successful candidate will be proficient in a wide range of analytical methods and the use of bioinformatics/genetics software for analyzing and interpreting various types of data.CategoryScientific ID2021-1034 ClassificationOn-going