The laboratory of Dr. Taosheng Chen studies the roles of nuclear receptors PXR and CAR in regulating drug-induced liver toxicity, tumorigenesis, and cancer drug resistance. We develop novel chemical probes/therapeutic leads by using a multidisciplinary approach (biology, chemistry and structural biology), and use them to interrogate the function of PXR, CAR and CYP3A in […]
Read MoreStudy finds early signatures of the social brain Humans use an ability known as theory of mind every time they make inferences about someone else’s mental state — what the other person believes, what they want, or why they are feeling happy, angry, or scared. Behavioral studies have suggested that children begin succeeding at a […]
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